Economic issues play a major role in the fight to eradicate smoking, particularly in an era of major advances in harm reduction. The Economics of Ending Smoking webinar series was conceived by the Foundation for a Smoke-Free World as a means to bring together stakeholders from around the world – particularly in LMIC countries where the need is most critical. Current evidence and key strategies in the fight to eradicate smoking were discussed during weekly online forums held between May and November of 2020.